Friday, September 02, 2005
Presynaptic Inhibition
There may be a maintained depolarization of the presynaptic terminal, reducing the amplitude of an invading impulse and with it the amount of transmitter released from the terminal. The essential operating characteristic of this microcircuit is that the effect of an input A on a cell C may be reduced or abolished by B without there being any direct action of B on the cell C itself. Control of the input A to the dendrite or cell body can thus be much more specific. (SOB, p12)
There may be a maintained depolarization of the presynaptic terminal, reducing the amplitude of an invading impulse and with it the amount of transmitter released from the terminal. The essential operating characteristic of this microcircuit is that the effect of an input A on a cell C may be reduced or abolished by B without there being any direct action of B on the cell C itself. Control of the input A to the dendrite or cell body can thus be much more specific. (SOB, p12)